Odontoblast control of dental pulp inflammation triggered by cariogenic bacteria
نویسندگان
چکیده
1 Institut de Génomique Fonctionnelle de Lyon, Equipe Physiopathologie des Odontoblastes, Ecole Normale Supérieure de Lyon, CNRS UMR5242, Lyon, France 2 Faculté d’Odontologie, Université de Lyon, Université Lyon 1, Lyon, France 3 Hospices Civils de Lyon, Service de Consultations et Traitements Dentaires, Lyon, France 4 Faculté d’Odontologie, INSERM UMR1064, Centre de Recherche en Transplantation et Immunologie, Université de Nantes, Nantes, France 5 Laboratoires Expanscience, Epernon, France *Correspondence: [email protected]
منابع مشابه
Odontoblast layer structure alteration as a response to carious lesions
Background: Dental caries is a bacterial disease affecting the hard tissue of the teeth as well as the pulp. The human dental pulp consists of odontoblast which are organized as a densely packed cell layer. Odontoblasts is located at the periphery of the pulp; therefore, they are the first cells encountered by cariogenic bacteria and their products that are represented in the carious lesion. Pu...
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The penetration of cariogenic oral bacteria into enamel and dentin during the caries process triggers an immune/inflammatory response in the underlying pulp tissue, the reduction of which is considered a prerequisite to dentinogenesis-based pulp regeneration. If the role of odontoblasts in dentin formation is well known, their involvement in the antibacterial response of the dental pulp to cari...
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